2-Deoxy-scyllo-inosamine dehydrogenase (SAM-dependent)

Enzyme 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent) 1.1.99.38 2-deoxy-scyllo-inosamine dehydrogenase (SAM-dependent) (1.1.99.38, btrN (gene)) is an enzyme with systematic name 2-deoxy-scyllo-inosamine:S-adenosyl-L-methionine 1-oxidoreductase. Yokoyama K, Numakura M, Kudo F, Ohmori D, Eguchi T Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin Journal of the American Chemical Society 129 49 15147–55 December 2007 18001019 10.1021/ja072481t 2007JAChS.12915147Y Yokoyama K, Ohmori D, Kudo F, Eguchi T Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy Biochemistry 47 34 8950–60 August 2008 18672902 10.1021/bi800509x This enzyme catalyses the following chemical reaction 65% Q27133607 2-deoxy-scyllo-inosamine + S-adenosyl methionine reversible methionine methionine Q27133591 3-amino-2,3-dideoxy-scyllo-inosose + 5'-deoxyadenosine This enzyme participates in the biosynthetic pathway of the aminoglycoside antibiotics of the butirosin family.1.1.99.38 References External links 2-deoxy-scyllo-inosamine+dehydrogenase+(SAM-dependent) Biology no Category:EC 1.1.99