(R)-3-hydroxyacid-ester dehydrogenase

Class of enzymes (R)-3-hydroxyacid-ester dehydrogenase 1.1.1.279 114705-02-1 0047108 In enzymology, (R)-3-hydroxyacid-ester dehydrogenase (1.1.1.279) is an enzyme that catalyzes the chemical reaction 50% Q27102010 ethyl (R)-3-hydroxyhexanoate + NADP+ reversible H+ H+ Q27102838 ethyl 3-oxohexanoate + NADPH The two substrates of this enzyme are ethyl (R)-3-hydroxyhexanoate and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are ethyl 3-oxohexanoate, reduced NADPH, and a proton.1.1.1.279Heidlas J, Engel KH, Tressl R 1988 Purification and characterization of two oxidoreductases involved in the enantioselective reduction of 3-oxo, 4-oxo and 5-oxo esters in baker's yeast Eur. J. Biochem. 172 633–9 3280313 10.1111/j.1432-1033.1988.tb13936.x 3 free This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is ethyl-(R)-3-hydroxyhexanoate:NADP+ 3-oxidoreductase. This enzyme is also called 3-oxo ester (R)-reductase. See also (S)-3-hydroxyacid-ester dehydrogenase which acts on the enantiomer of the substrate References Biology no Category:EC 1.1.1 Category:NADPH-dependent enzymes Category:Enzymes of unknown structure