2-Methyl-MDA

Chemical compound changed 477214404 2-Methyl-MDA.svg skin-invert-image 250px Uncontrolled (but may be covered under the Federal Analogue Act in the United States and under similar bills in other countries) Oral changed ?? 691876-73-0 204916-87-0 (HCl) none 10104064 correct chemspider 8279591 correct EBI 6391 1-(4-methyl-1,3-benzodioxol-5-yl)propan-2-amine 11 15 1 2 O2COc1c2ccc(c1C)CC(C)N correct chemspider 1S/C11H15NO2/c1-7(12)5-9-3-4-10-11(8(9)2)14-6-13-10/h3-4,7H,5-6,12H2,1-2H3 correct chemspider WVACHJAKQMSYSU-UHFFFAOYSA-N 2-Methyl-3,4-methylenedioxyamphetamine (2-methyl-MDA) is an entactogen-related drug of the amphetamine class. It acts as a selective serotonin releasing agent (SSRA), with IC50 values of 93nM, 12,000nM, and 1,937nM for serotonin, dopamine, and norepinephrine efflux.Parker MA, Marona-Lewicka D, Kurrasch D, Shulgin AT, Nichols DE Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA) Journal of Medicinal Chemistry 41 6 1001–5 March 1998 9526575 10.1021/jm9705925 2-Methyl-MDA is more potent than MDA and 5-methyl-MDA. However, it is slightly more selective for serotonin over dopamine and norepinephrine release in comparison to 5-methyl-MDA. See also Substituted methylenedioxyphenethylamine 2,6-di-tert-butylphenol References External links 2-Methyl-MDA - Isomer Design Category:Entactogens Category:Methylenedioxyamphetamines Category:Serotonin releasing agents