2-dehydropantolactone reductase (A-specific)

Class of enzymes 2-dehydropantolactone reductase (A-specific) 1.1.1.168 37211-75-9 0047011 In enzymology, 2-dehydropantolactone reductase (A-specific) (1.1.1.168) is an enzyme that catalyzes the chemical reaction 50% Q27102042 (R)-pantolactone + NADP+ reversible H+ H+ Q27103050 2-dehydropantolactone + NADPH The two substrates of this enzyme are (R)-pantolactone and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are 2-dehydropantolactone, reduced NADPH, and a proton.1.1.1.168 ((King HL Jr)), Dyar RE, Wilken DR Aug 10, 1974 Ketopantoyl lactone and ketopantoic acid reductases: Characterization of the reactions and purification of two forms of ketopantoyl lactone reductase J. Biol. Chem. 249 15 4689–4695 10.1016/S0021-9258(19)42375-2 free 4603075Wilken DR, ((King HL Jr)), Dyar RE March 25, 1975 Ketopantoic acid and ketopantoyl lactone reductases: Stereospecificity of transfer of hydrogen from reduced nicotinamide adenine dinucleotide phosphate J. Biol. Chem. 250 6 2311–2314 10.1016/S0021-9258(19)41717-1 free 234966 This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-pantolactone:NADP+ oxidoreductase (A-specific). Other names in common use include 2-oxopantoyl lactone reductase, ketopantoyl lactone reductase, 2-ketopantoyl lactone reductase, and 2-dehydropantoyl-lactone reductase (A-specific). References Biology no Category:EC 1.1.1 Category:NADPH-dependent enzymes Category:Enzymes of unknown structure