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2,3-Dimethoxyphenethylamine
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2,3-Dimethoxyphenethylamine.svg skin-invert-image 225px None 3213-29-4 137858 121507 LUW5Z6DJ9Q 2,3-DMPEA; DMPEA-2 2-(2,3-dimethoxyphenyl)ethanamine 10 15 1 2 COC1=CC=CC(=C1OC)CCN 1S/C10H15NO2/c1-12-9-5-3-4-8(6-7-11)10(9)13-2/h3-5H,6-7,11H2,1-2H3 XKBUFTXNLBWTFP-UHFFFAOYSA-N
2,3-Dimethoxyphenethylamine (2,3-DMPEA), also known as DMPEA-2, is a drug of the phenethylamine family related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). Shulgin A, Manning T, Daley PF #46. 2,3-DMPEA 81–82 https://archive.org/details/shulgin-index-vol-1/page/81/mode/1up The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds Transform Press Berkeley, CA 1 2011 978-0-9630096-3-0 709667010 Clark LC, Benington F, Morin RD The effects of ring-methoxyl groups on biological deamination of phenethylamines J Med Chem 8 3 353–355 May 1965 14323146 10.1021/jm00327a016 It is one of the positional isomers of dimethoxyphenethylamine.
In contrast to various other phenethylamines like β-phenethylamine and amphetamine, it showed little activity in terms of induction of norepinephrine release in vitro. Benington F, Morin RD The chemorelease of norepinephrine from mouse hearts by substituted amphetamines J Med Chem 11 4 896–897 July 1968 5677681 10.1021/jm00310a048 The effects of 2,3-DMPEA in humans have not been reported and are unknown.
2,3-DMPEA was first described in the scientific literature by at least 1965. It was included as an entry in Alexander Shulgin's 2011 book The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds.
See also
Substituted methoxyphenethylamine
Dimethoxyphenethylamine
2,3-Dimethoxyamphetamine
Isomescaline (2,3,4-trimethoxyphenethylamine)
References
External links
2,3-DMPEA - Isomer Design
2,3-DMPEA - The Shulgin Index
Category:Methoxyphenethylamines
Category:Dimethoxyphenyl compounds