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2-methylisoborneol synthase
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Class of enzymes
2-methylisoborneol synthase 4.2.3.118
2-methylisoborneol synthase (EC 4.2.3.118, sco7700, 2-MIB cyclase, MIB synthase, MIBS) is an enzyme with systematic name (E)-2-methylgeranyl-diphosphate diphosphate-lyase (cyclizing, 2-methylisoborneol-forming). Wang CM, Cane DE Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor Journal of the American Chemical Society 130 28 8908–9 July 2008 18563898 3023297 10.1021/ja803639g 2008JAChS.130.8908W Komatsu M, Tsuda M, Omura S, Oikawa H, Ikeda H Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol Proceedings of the National Academy of Sciences of the United States of America 105 21 7422–7 May 2008 18492804 2387273 10.1073/pnas.0802312105 2008PNAS..105.7422K free Giglio S, Chou WK, Ikeda H, Cane DE, Monis PT Biosynthesis of 2-methylisoborneol in cyanobacteria Environmental Science & Technology 45 3 992–8 February 2011 21174459 3699865 10.1021/es102992p 2011EnST...45..992G This enzyme catalyses the following chemical reaction
(E)-2-methylgeranyl diphosphate + H2O 2-methylisoborneol + diphosphate
The product, 2-methylisoborneol, is a characteristic odiferous compound with a musty smell produced by soil microorganisms.
References
External links
2-methylisoborneol+synthase
Biology no
Category:EC 4.2.3