2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase

Class of enzymes 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase 2.2.1.10 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase (2.2.1.10, ADH synthase, ADHS, MJ0400 (gene)) is an enzyme with systematic name L-aspartate 4-semialdehyde:1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate methylglyoxaltransferase. White RH L-Aspartate semialdehyde and a 6-deoxy-5-ketohexose 1-phosphate are the precursors to the aromatic amino acids in Methanocaldococcus jannaschii Biochemistry 43 23 7618–27 June 2004 15182204 10.1021/bi0495127 Samland AK, Wang M, Sprenger GA MJ0400 from Methanocaldococcus jannaschii exhibits fructose-1,6-bisphosphate aldolase activity FEMS Microbiology Letters 281 1 36–41 April 2008 18318840 10.1111/j.1574-6968.2008.01079.x free Morar M, White RH, Ealick SE Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids Biochemistry 46 37 10562–71 September 2007 17713928 10.1021/bi700934v This enzyme catalyses the following chemical reaction L-aspartate 4-semialdehyde + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + 2,3-dioxopropyl phosphate The enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate. center|thumb|615x615px|Chemical reaction catalyzed by 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase References External links 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate+synthase Biology no Category:EC 2.2.1