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1,3-Difluoro-2-propanol
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changed changed 477205240 1,3-Difluoro-2-propanol.svg 120px 1,3-Difluoro-2-propanol-3D-balls-by-AHRLS-2012.png 120px 1,3-Difluoro-2-propanol-3D-vdW-by-AHRLS-2012.png 120px 1,3-Difluoropropan-2-ol correct chemspider 61300 1/C3H6F2O/c4-1-3(6)2-5/h3,6H,1-2H2 FCC(O)CF PVDLUGWWIOGCNH-UHFFFAOYAJ correct chemspider 1S/C3H6F2O/c4-1-3(6)2-5/h3,6H,1-2H2 correct chemspider PVDLUGWWIOGCNH-UHFFFAOYSA-N changed ?? 453-13-4 correct FDA R8ZM2LQG7K 67985 OC(CF)CF 3 6 2 1 1.24 g/cm3 (at 25 °C)Sigma Aldrich 54 to 55 42
1,3-Difluoro-2-propanol is a metabolic poison which disrupts the citric acid cycle and is used as a rodenticide, similar to sodium fluoroacetate. It is the main ingredient (along with 1-chloro-3-fluoro-2-propanol) in the rodenticide product Gliftor (or Glyftor) which was widely used in the former USSR Buklan AI, Kravets AF [Gliftor poisoning] ru Sudebno-Meditsinskaia Ekspertiza 29 1 55–6 1986 3961873 Feldwick MG, Noakes PS, Prause U, Mead RJ, Kostyniak PJ The biochemical toxicology of 1,3-difluoro-2-propanol, the major ingredient of the pesticide gliftor: the potential of 4-methylpyrazole as an antidote Journal of Biochemical and Molecular Toxicology 12 1 41–52 1998 9414486 10.1002/(SICI)1099-0461(1998)12:1<41::AID-JBT6>3.0.CO;2-P 29455648 Menon KI, Feldwick MG, Noakes PS, Mead RJ The mode of toxic action of the pesticide gliftor: the metabolism of 1,3-difluoroacetone to (−)-erythro-fluorocitrate Journal of Biochemical and Molecular Toxicology 15 1 47–54 2001 11170315 10.1002/1099-0461(2001)15:1<47::AID-JBT6>3.0.CO;2-E 9064673 and still approved in China.Wood Alan Gliftor http://www.alanwood.net/pesticides/gliftor.html Compendium of Pesticide Common Names 14 June 2021
See also
1,3-Dichloro-2-propanol
References
Category:Rodenticides
Category:Fluorohydrins
Category:Respiratory toxins
Category:Secondary alcohols