(S)-2-methylmalate dehydratase

Class of enzymes (S)-2-methylmalate dehydratase 4.2.1.34 9027-94-5 0047510 The enzyme (S)-2-methylmalate dehydratase (4.2.1.34) catalyzes the chemical reaction: (S)-2-methylmalate 2-methylfumarate + H2O This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (S)-2-methylmalate hydro-lyase (2-methylfumarate-forming). Other names in common use include mesaconate hydratase, (+)-citramalate hydro-lyase, L-citramalate hydrolase, citramalate dehydratase, (+)-citramalic hydro-lyase, mesaconate mesaconase, mesaconase, and (S)-2-methylmalate hydro-lyase. This enzyme participates in c5-branched dibasic acid metabolism. In addition, the family of lyases which is also an enzyme catalyzes the breaking the elimination reaction of the variety of amounts of chemical bonds from hydrolysis (a substitution reaction ) and oxidation, which forms a new double bond or a new ring structure. References 1 Blair AH, Barker HA 1966 Assay and purification of (+)-citramalate hydro-lyase components from Clostridium tetanomorphum J. Biol. Chem. 241 400–8 5903732 2 10.1016/S0021-9258(18)96931-0 free Wang CC, Barker HA 1969 Purification and properties of L-citramalate hydrolyase J. Biol. Chem. 244 2516–26 5769987 10 10.1016/S0021-9258(18)83432-9 free Biology no Category:EC 4.2.1 Category:Enzymes of unknown structure