2-oxo-acid reductase

Class of enzymes 2-oxo-acid reductase 1.1.99.30 115299-99-5 In enzymology, a 2-oxo-acid reductase (1.1.99.30) is an enzyme that catalyzes the chemical reaction a (2R)-hydroxy-carboxylate + acceptor a 2-oxo-carboxylate + reduced acceptor Thus, the two substrates of this enzyme are (2R)-hydroxy-carboxylate and acceptor, whereas its two products are 2-oxo-carboxylate and reduced acceptor. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (2R)-hydroxy-carboxylate:acceptor oxidoreductase. Other names in common use include (2R)-hydroxycarboxylate-viologen-oxidoreductase, HVOR, and 2-oxoacid reductase. References 1 Trautwein T, Krauss F, Lottspeich F, Simon H 1994 The (2R)-hydroxycarboxylate-viologen-oxidoreductase from Proteus vulgaris is a molybdenum-containing iron-sulphur protein Eur. J. Biochem. 222 1025–32 8026480 10.1111/j.1432-1033.1994.tb18954.x 3 free Neumann S, Simon H 1985 On a non-pyridine nucleotide-dependent 2-oxoacid reductase of broad specificity from two Proteus species FEBS Lett. 167 1 29–32 10.1016/0014-5793(84)80826-1 free Biology no Category:EC 1.1.99 Category:Enzymes of unknown structure