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(deoxy)nucleoside-phosphate kinase
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Class of enzymes
(deoxy)nucleoside-phosphate kinase 2.7.4.13 37278-20-9 0047507
In enzymology, a (deoxy)nucleoside-phosphate kinase (2.7.4.13) is an enzyme that catalyzes the chemical reaction
ATP + deoxynucleoside phosphate ADP + deoxynucleoside diphosphate
Thus, the two substrates of this enzyme are ATP and deoxynucleoside phosphate, whereas its two products are ADP and deoxynucleoside diphosphate.BESSMAN MJ, HERRIOTT ST, ORR MJ 1965 The Enzymology of Virus-Infected Bacteria. Vi. Purification and Properties of the Deoxynucleotide Kinase Induced by Bacteriophage T5 J. Biol. Chem. 240 439–45 10.1016/S0021-9258(18)97668-4 free 14253449
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:deoxynucleoside-phosphate phosphotransferase. Other names in common use include deoxynucleoside monophosphate kinase, deoxyribonucleoside monophosphokinase, and deoxynucleoside-5'-monophosphate kinase.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1DEK and 1DEL.
References
Biology no
Category:EC 2.7.4
Category:Enzymes of known structure