2-hydroxycyclohexanone 2-monooxygenase

Class of enzymes 2-hydroxycyclohexanone 2-monooxygenase 1.14.13.66 62628-31-3 0047095 2-hydroxycyclohexanone 2-monooxygenase (1.14.13.66) is an enzyme that catalyzes the chemical reaction 65% Q27102692 2-hydroxycyclohexan-1-one + NADPH O2 + H+ H2O Q27102198 6-hydroxyhexano-6-lactone + NADP+ The four substrates of this enzyme are 2-hydroxycyclohexan-1-one, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen, and a proton. Its products are 6-hydroxyhexano-6-lactone, oxidised NADP+, and water.1.14.13.66Davey JF, Trudgill PW 1977 The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species Eur. J. Biochem. 74 115–27 856571 10.1111/j.1432-1033.1977.tb11373.x 1 free This enzyme is an oxidoreductase, acting on paired donors, with molecular oxygen as oxidant and incorporating one of its atoms. The systematic name of this enzyme class is 2-hydroxycyclohexan-1-one,NADPH:oxygen 2-oxidoreductase (1,2-lactonizing). The product spontaneously forms 6-oxohexanoic acid and in Acinetobacter this can be further oxidised to adipic acid. 65% Q27102198 6-hydroxyhexano-6-lactone Q27105685 6-oxohexanoic acid adipic acid References Biology no Category:EC 1.14.13 Category:NADPH-dependent enzymes Category:Enzymes of unknown structure