1-aminocyclopropane-1-carboxylate deaminase

InterPro Family 1-aminocyclopropane-1-carboxylate deaminase 3.5.99.7 69553-48-6 0008660 In enzymology, a 1-aminocyclopropane-1-carboxylate deaminase (3.5.99.7) is an enzyme that catalyzes the chemical reaction 1-aminocyclopropane-1-carboxylate + H2O 2-oxobutanoate + NH3 Thus, the two substrates of this enzyme are 1-aminocyclopropane-1-carboxylate and H2O, whereas its two products are 2-oxobutanoate and NH3. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 1-aminocyclopropane-1-carboxylate aminohydrolase (isomerizing). This enzyme is also called 1-aminocyclopropane-1-carboxylate endolyase (deaminating). This enzyme participates in propanoate metabolism. It employs one cofactor, pyridoxal phosphate. Structural studies As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1RQX, 1TYZ, 1TZ2, 1TZJ, 1TZK, and 1TZM. References 1 Honma M, Shimomura T 1978 Metabolism of 1-aminocyclopropane-1-carboxylic acid Agric. Biol. Chem. 42 10 1825–1831 10.1271/bbb1961.42.1825 free Wakatsuki S, Yokoi D, Murakami T, Honma M, Tanaka I 2000 Crystal structure of 1-aminocyclopropane-1-carboxylate deaminase from Hansenula saturnus J. Biol. Chem. 275 34557–34565 10.1074/jbc.M004681200 10938279 44 free 11094/73646 free Biology no Category:EC 3.5.99 Category:Pyridoxal phosphate enzymes Category:Enzymes of known structure