411 REFERENCE · Wikipedia
2-Chlorobenzaldehyde
Reference material by Wikipedia contributors. This retains its source identity and is not 411 news reporting.
Chemical compound
2-Chlorobenzaldehyde 2-Chlorbenzaldehyd.svg 120px 2-Chlorobenzaldehyde o-Chlorobenzaldehyde 89-98-5 21106014 6996 1547989 201-956-3 CU5075000 3265 QHR24X1LXK 1S/C7H5ClO/c8-7-4-2-1-3-6(7)5-9/h1-5H FPYUJUBAXZAQNL-UHFFFAOYSA-N c1ccc(c(c1)C=O)Cl 7 5 1 1 Clear colourless to pale yellow oily liquid 9-12 209-215 1.25 Insoluble Slightly soluble in Acetonitrile, sparingly soluble in DMSO 05 07 Danger 290 302 314 317 234 260 261 264 270 272 280 301+312 301+330+331 302+352 303+361+353 304+340 305+351+338 310 321 330 333+313 363 390 404 405 501 87 385
2-Chlorobenzaldehyde (o-chlorobenzaldehyde) is an organic compound with the formula ClC6H4CHO. It is one of three isomeric monochlorinated benzaldehyde. 3-Chlorobenzaldehyde and 4-chlorobenzaldehyde are the other isomers. Whereas benzaldehyde is prone to autoxidation, the 2-chloro derivatives are more air-stable.
Synthesis and uses
It is produced by hydrolysis of 2-chlorobenzal chloride:10.1002/14356007.a03_463.pub2 Benzaldehyde Ullmann's Encyclopedia of Industrial Chemistry 2011 Brühne Friedrich Wright Elaine 978-3-527-30385-4
ClC6H4CHCl2 + H2O -> ClC6H4CHO + 2 HCl
2-Chlorobenzaldehyde is used in production of CS gas. It reacts with malononitrile to form CS.Synthesis of ortho-chlorobenzalmalononitrile https://patents.google.com/patent/US3963770A
2-Chlorobenzaldehyde is used in the synthesis of: Clopidogrel, Amlodipine, Levamlodipine, Zotepine, Clobenzorex, Tradipitant, Lodaxaprine, Bay-k-9320, SK 609, Sephin 1 & YC 170.
References
Category:Benzaldehydes
Category:2-Chlorophenyl compounds