2,3-Dihydroxybenzoic acid

changed 477198527 2,3-Dihydroxybenzoesäure.svg 100px 2,3-Dihydroxybenzoic acid Hypogallic acid 2-Pyrocatechuic acid o-Pyrocatechuic acid 2,3-DHBA 2,3-DHB 18 19 correct kegg C00196 1/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11) correct drugbank DB01672 O=C(O)c1cccc(O)c1O GLDQAMYCGOIJDV-UHFFFAOYAE c1cc(c(c(c1)O)O)C(=O)O correct EBI 18026 correct EBI 1432 correct chemspider 1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11) correct chemspider GLDQAMYCGOIJDV-UHFFFAOYSA-N correct CAS 303-38-8 correct FDA 70D5FBB392 correct chemspider Haynes Haynes, William M. 2016 CRC Handbook of Chemistry and Physics 97th CRC Press https://ia800704.us.archive.org/27/items/CRCHandbookOfChemistryAndPhysics97thEdition2016/CRC%20Handbook%20of%20Chemistry%20and%20Physics%20-%2097th%20Edition%20%282016%29.pdf?page=3-190 9781498754293 3 190 7 6 4 Colorless solid 1.542 g/cm3 (20 °C) 205 soluble soluble ethanol soluble diethyl ether soluble acetone 2,4-Dihydroxybenzoic acid 2,5-Dihydroxybenzoic acid 2,6-Dihydroxybenzoic acid 3,4-Dihydroxybenzoic acid 3,5-Dihydroxybenzoic acid 2,3-Dihydroxybenzoic acid is a dihydroxybenzoic acid, a type of organic compound. It occurs naturally in various plants, bacteria, and fungi. Uses It is a potentially useful iron-chelating drug and has antimicrobial properties. The identification of 2,3-dihroxybenzoic acid as a potentially useful iron-chelating drug Graziano, J. H. Grady, R. W. Cerami, A. Journal of Pharmacology and Experimental Therapeutics 1974 190 3 570–575 4416298 http://jpet.aspetjournals.org/content/190/3/570.shortGeorge, Shibumon PJ, Benny Kuriakose, Sunny George, Cincy https://innovareacademics.in/journal/ajpcr/Vol4Issue1/227.pdf Antibiotic activity of 2,3-dihydroxybenzoic acid isolated from Flacourtia inermis fruit against multidrug resistant bacteria Asian Journal of Pharmaceutical and Clinical Research 4 1 2011September 2025 Occurrence It is found in Phyllanthus acidusSeptember 2025 and in the aquatic fern Salvinia molesta. Choudhary M. I. Naheed N. Abbaskhan A. Musharraf S. G. Siddiqui H. Atta-Ur-Rahman 10.1016/j.phytochem.2007.10.028 Phenolic and other constituents of fresh water fern Salvinia molesta Phytochemistry 69 4 1018–1023 2008 18177906 It is also abundant in the fruits of Flacourtia inermis. The colorless solid occurs naturally, being formed via the shikimate pathway.September 2025 It is incorporated into various siderophores, which are molecules that strongly complex iron ions for absorption into bacteria. 2,3-DHB consists of a catechol group, which upon deprotonation binds iron centers very strongly, and the carboxylic acid group by which the ring attaches to various scaffolds through amide bonds. A famous high affinity siderophore is enterochelin, which contains three dihydroxybenzoyl substituents linked to the depsipeptide of serine.O'Brien, I. G. Cox, G. B. Gibson, F. Biologically active compounds containing 2,3-dihydroxybenzoic acid and serine formed by Escherichia coli Biochimica et Biophysica Acta (BBA) - General Subjects 1970 201 453–60 4908639 3 10.1016/0304-4165(70)90165-0 2,3-Dihydroxybenzoic acid is also a product of human aspirin metabolism. Grootveld M. Halliwell B. 10.1016/0006-2952(88)90729-0 2,3-Dihydroxybenzoic acid is a product of human aspirin metabolism Biochemical Pharmacology 37 2 271–280 1988 3342084 References Category:Dihydroxybenzoic acids Category:Salicylic acids Category:Chelating agents Category:Catechols Category:Human drug metabolites