19,20-Dihydroervahanine A

December 2024 December 2025 CAS has two versions of the stereochemistry for this compound, both incompatible with the version presented here; the structure should be double-checked against primary sources 19,20-Dihydroervahanine A.svg skin-invert-image 250px Chemical structure of 19,20-dihydroervahanine A Methyl (1S,15R,17S,18S)-17-ethyl-6-[(1S,12R,14S,15S,18S)-15-ethyl-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate 175478-70-3 28501024 70687579 2018162 CC[C@H]1C[C@H]2C[C@@]3([C@H]1N(C2)CCC4=C3NC5=C4C=CC(=C5)[C@H]6C[C@@H]7[C@@H](CN([C@H](C7C(=O)OC)CC8=C6NC9=CC=CC=C89)C)CC)C(=O)OC InChI=1S/C42H52N4O4/c1-6-24-16-23-20-42(41(48)50-5)38-29(14-15-46(21-23)39(24)42)28-13-12-26(17-34(28)44-38)31-18-30-25(7-2)22-45(3)35(36(30)40(47)49-4)19-32-27-10-8-9-11-33(27)43-37(31)32/h8-13,17,23-25,30-31,35-36,39,43-44H,6-7,14-16,18-22H2,1-5H3/t23-,24-,25+,30+,31+,35-,36?,39-,42+/m0/s1 PKHROTRJQXGCIW-XIVABZEMSA-N 42 52 4 4 19,20-Dihydroervahanine A is an alkaloid, a natural product which is found in the root of the Southeast Asian plant Tabernaemontana divaricata. Ingkaninan K, Changwijit K, Suwanborirux K Vobasinyl-iboga bisindole alkaloids, potent acetylcholinesterase inhibitors from Tabernaemontana divaricata root The Journal of Pharmacy and Pharmacology 58 6 847–52 June 2006 16734986 10.1211/jpp.58.6.0015 37975644 free It inhibits acetylcholinesterase in vitro more potently than galantamine. See also Coronaridine Ibogamine References Category:Tryptamine alkaloids Category:Acetylcholinesterase inhibitors Category:Neurotoxins