18-Deoxyaldosterone

Chemical compound 18-Deoxyaldosterone.svg skin-invert-image changed ChemSpider 2507-88-2 Antimineralocorticoid 188963 164193 correct FDA S4YT68R2XR 21 28 4 C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@@H]4CC5([C@H]3CC[C@@H]5C(=O)CO)CO4 1S/C21H28O4/c1-20-7-6-13(23)8-12(20)2-3-14-15-4-5-16(17(24)10-22)21(15)9-18(19(14)20)25-11-21/h8,14-16,18-19,22H,2-7,9-11H2,1H3/t14-,15-,16+,18-,19+,20-,21?/m0/s1 ZEBLTAXSHAKMDJ-QBSCYWOBSA-N 11β,18-epoxy-21-hydroxypregn-4-ene-3,20-dione, 11β-11,18-epoxy-21-hydroxypregn-4-ene-3,20-dione, 11β,18-epoxy-21-hydroxy-progesterone, 21-hydroxy-11β,18-oxido-4-pregnene-3,20-dionehttps://pubchem.ncbi.nlm.nih.gov/compound/21125567 (11beta)-11,18-Epoxy-21-hydroxypregn-4-ene-3,20-dione 18-Deoxyaldosterone is a steroidal antimineralocorticoid with mixed agonist–antagonist but predominantly antagonistic activity at the mineralocorticoid receptor. Duax WL, Griffin JF, Strong PD, Funder JW, Ulick S Molecular structure of 18-deoxyaldosterone and its relationship to receptor binding and activity Journal of the American Chemical Society 104 25 1982 7291–7293 0002-7863 10.1021/ja00389a063 1982JAChS.104.7291D References Category:Primary alcohols Category:Antimineralocorticoids Category:Diketones Category:Pregnanes Category:Enones