2-Indanone oxime

October 2026 October 2026 October 2026 2-INDANAOXIMI.svg N-(1,3-dihydroinden-2-ylidene)hydroxylamine correct chemspider 69326 correct FDA 9OUM5TX75K correct chemspider 1S/C9H9NO/c11-10-9-5-7-3-1-2-4-8(7)6-9/h1-4,11H,5-6H2 correct chemspider UJLFLOAXKVGYIA-UHFFFAOYSA-N correct CAS 3349-63-1 76875 correct kegg C14639 34291 222-105-2 C1C(=NO)CC2=CC=CC=C21 1S/C9H9NO/c11-10-9-5-7-3-1-2-4-8(7)6-9/h1-4,11H,5-6H2 UJLFLOAXKVGYIA-UHFFFAOYSA-N 9 9 1 1 152-154 2-Indanone oxime is a bicyclic nitrogen-containing organic compound that is an indane derivative where the carbonyl oxygen of the parent ketone at the second carbon atom has been replaced by an oxime; this agent is used as a precursor for 2-aminoindanes. Use Synthesis of 2-aminoindanes The reaction proceeds via the sequential reduction of the oxime group (C=N−OH) to a free amino group (NH2). A key challenge in classic oxime hydrogenation is the occurrence of side reactions. By conducting catalytic hydrogenation of 2-indanone oxime with hydrogen at 20–70 psi at room temperature, using non-pyrophoric supported palladium in acetic acid or ethyl acetate in the presence of sulfuric acid—which blocks side reactions through in situ salt formation—a selective yield of the target hydrochloride.US3196181A Catalytic reduction of 2-oximinoindane to 2-amino-indane 1965-07-20 Edward Ferdinand Rosen William Huebner Charles https://patents.google.com/patent/US3196181A/en References Further reading Rylander Paul Nels Catalytic Hydrogenation over Platinum Metals 1967 Elsevier Science 978-0-323-14586-2 Burlington 147–149 Category:Indenes Category:Bicyclic compounds Category:Oximes